BDBM82310 Purine, 5

SMILES FC(F)(F)c1cccc(CNc2nc(NCc3ccc(cc3)N(=O)=O)c3[nH]cnc3n2)c1

InChI Key InChIKey=DDSBPUYZPWNNGH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 82310   

TargetInositol-trisphosphate 3-kinase A(Human)
New York University

LigandPNGBDBM82310(Purine, 5)
Affinity DataKi:  4.30E+3nM ΔG°:  -7.61kcal/mole IC50: 1.02E+4nMpH: 8.0 T: 2°CAssay Description:IP3K reactions were carried out in a 100ul solution that contained Tris-Cl, EGTA, ATP, DTT, 2,3-diphosphoglycerate, D-l(1,4,5)P3, [3H]-l(1,4,5)P3 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details Article
PubMed