BDBM81767 15-28-Somatostatin-28::CAS_38916-34-6::CB6417646::Somatostatin-14
SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O
InChI Key InChIKey=NHXLMOGPVYXJNR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 144 hits for monomerid = 81767
Affinity DataIC50: 6nMAssay Description:Compound was evaluated for the inhibition of binding of [3H]naloxone toOpioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]-DPDPE binding to Opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR2bMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor mSSTR3More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor hSSTR4More data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Tested for inhibition of radioligand binding to cloned somatostatin receptor rSSTR5More data for this Ligand-Target Pair
Affinity DataEC50: 0.190nMAssay Description:Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst5 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Inhibition of forskolin-induced cAMP accumulation in CHO-K1 cells expressing human sst2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0650nMAssay Description:Effective concentration on human somatostatin receptor 5More data for this Ligand-Target Pair
Affinity DataIC50: 0.0740nMAssay Description:Displacement of [125I]Tyr11-somatostatin-14 from somatostatin receptor in mouse AtT20 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst3 receptor in CCL39 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst4 receptor in CCL39 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst5 receptor in HEK293 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
Affinity DataEC50: 0.780nMAssay Description:Agonist activity at human sst3 receptor expressed in CCL39 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Displacement of 125I-[LTT]-SRIF-28 from human sst2 receptor in CCL39 cells after 2 hrs by autoradiographyMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Compound was tested for its binding affinity against somatostatin receptors on AtT-20 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Compound was tested for its inhibitory effect against somatostatin receptor in rat cortex membrane using [125I]Tyr3-octreotide as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataKd: 0.214nMAssay Description:Binding assay at human somatostatin receptor 3 (hsst3) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Affinity DataKd: 0.832nMAssay Description:Binding assay at human somatostatin receptor 1 (hsst1) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Affinity DataKd: 0.0871nMAssay Description:Binding assay at human somatostatin receptor 2 (hsst2) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Affinity DataKd: 4.10nMAssay Description:Binding assay at human somatostatin receptor 4 (hsst4) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Affinity DataKd: 0.977nMAssay Description:Binding assay at human somatostatin receptor 5 (hsst5) expressed in CCL-39 cells using LTT-CST-14-(Tyr10) as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]-[LTT]-SS28 from human SST1 receptor expressed in CHO cells after 2 hrs by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]-[LTT]-SS28 from human SST4 receptor expressed in Chinese hamster CCL-39 cells after 2 hrs by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]-[LTT]-SS28 from human SST2 receptor expressed in Chinese hamster CCL-39 cells after 2 hrs by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]-[LTT]-SS28 from human SST5 receptor expressed in HEK293 cells after 2 hrs by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]-[LTT]-SS28 from human SST3 receptor expressed in Chinese hamster CCL-39 cells after 2 hrs by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of human SSTR5 by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human SSTR4 by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.00160nMAssay Description:Displacement of [125I]-somatostatin from human SSTR2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0490nMAssay Description:Inhibition of human sst2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0830nMAssay Description:Inhibitory constant against human sst2 receptor at a dose of 10 uMMore data for this Ligand-Target Pair