BDBM81519 CAS_117690-79-6::CGS 23356::CHEMBL15766::LY 255283

SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1

InChI Key InChIKey=WCGXJPFHTHQNJL-UHFFFAOYSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 81519   

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataIC50: 85nMAssay Description:Binding affinity against LTB4 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataIC50: 85.1nMAssay Description:Inhibition of [3H]Leukotriene B4 binding to human PMNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataIC50: 87nMAssay Description:Compound was tested for inhibitory activity against human neutrophil LTB4 receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataIC50: 3.52E+4nMAssay Description:Antagonist activity at GST-tagged FXRalpha LBD (unknown origin) assessed as inhibition of CDCA-induced bio-SRC-1 recruitment after 30 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataIC50: 85nMAssay Description:In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetLeukotriene B4 receptor 2(Human)
Ciba-Geigy

Curated by PDSP Ki Database
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataKi:  66nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2011
Entry Details
PubMed
TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataKi:  77nMAssay Description:In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetLeukotriene B4 receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataKi:  78nMAssay Description:Binding affinity against LTB4 receptor in guinea pig membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetLeukotriene B4 receptor 2(Human)
Ciba-Geigy

Curated by PDSP Ki Database
LigandPNGBDBM81519(LY 255283 | CHEMBL15766 | CAS_117690-79-6 | CGS 23...)
Affinity DataKi:  116nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2011
Entry Details
PubMed