BDBM81359 NadD inhibitor 1_03::US8785499, 1_03

SMILES Brc1ccc(NC(=O)CCCC(=O)N\N=C\c2c3ccccc3cc3ccccc23)cc1

InChI Key InChIKey=OCIRIMJWKFJKDF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 81359   

TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81359(US8785499, 1_03 | NadD inhibitor 1_03)
Affinity DataIC50: 1.80E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetProbable nicotinate-nucleotide adenylyltransferase(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM81359(US8785499, 1_03 | NadD inhibitor 1_03)
Affinity DataIC50: 3.30E+4nMAssay Description:The enzymatic assay was masured at fixed NaMN and ATP concentration (equal to two-fold km values)with various concentration of inhibitory compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetNicotinate-nucleotide adenylyltransferase(Escherichia coli (strain K12))
Burnham Institute For Medical Research

LigandPNGBDBM81359(US8785499, 1_03 | NadD inhibitor 1_03)
Affinity DataIC50: 1.80E+4nMpH: 7.5 T: 2°CAssay Description:A general phosphate detection assay method using Malachite Green reagent was adapted to measure the activity of NaMN adenylyltransferaseA14. Briefly,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent