BDBM81346 CHEMBL538798::M9440 (Me-3,4-dephostatin)

SMILES CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc1ccccc1

InChI Key InChIKey=JSASWRWALCMOQP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 81346   

LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:In order to eliminated fluorescence interference, chemicals were subjected to a secondary screening using colorimetric BP incorporation assay. TGase...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 79.4nMAssay Description:In vitro inhibition of Janus kinase 3.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of Janus kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 80nMAssay Description:Inhibition of JAK3 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase, liver(Guinea pig)
Institute of Physical and Chemical Research (Riken)

Curated by ChEMBL
LigandPNGBDBM81346(CHEMBL538798 | M9440 (Me-3,4-dephostatin))
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of guinea pig liver transglutaminaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed