BDBM8080 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine deriv. 8k::4-(5-chloro-2,4-dimethyl-1H-pyrrol-3-yl)-N-(4-fluorophenyl)pyrimidin-2-amine

SMILES Cc1[nH]c(Cl)c(C)c1-c1ccnc(Nc2ccc(F)cc2)n1

InChI Key InChIKey=QRXPIPWIGBYIFY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8080   

LigandPNGBDBM8080(4-(5-chloro-2,4-dimethyl-1H-pyrrol-3-yl)-N-(4-fluo...)
Affinity DataKi:  360nM ΔG°:  -8.93kcal/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM8080(4-(5-chloro-2,4-dimethyl-1H-pyrrol-3-yl)-N-(4-fluo...)
Affinity DataKi:  1.91E+3nM ΔG°:  -7.93kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed