BDBM8071 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine deriv. 8b::3,5-dimethyl-4-{2-[(3-nitrophenyl)amino]pyrimidin-4-yl}-1H-pyrrole-2-carbonitrile

SMILES Cc1[nH]c(C#N)c(C)c1-c1ccnc(Nc2cccc(c2)N(=O)=O)n1

InChI Key InChIKey=QMDPRICJPXKZCF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8071   

LigandPNGBDBM8071(3,5-dimethyl-4-{2-[(3-nitrophenyl)amino]pyrimidin-...)
Affinity DataKi:  140nM ΔG°:  -9.50kcal/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM8071(3,5-dimethyl-4-{2-[(3-nitrophenyl)amino]pyrimidin-...)
Affinity DataKi:  960nM ΔG°:  -8.34kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed