BDBM8042 (3-Chlorophenyl)-[4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-yl]amine::2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 13::N-(3-chlorophenyl)-4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine

SMILES Cc1nc(C)c(s1)-c1ccnc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=CPJICALSLDLRJP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8042   

LigandPNGBDBM8042((3-Chlorophenyl)-[4-(2,4-dimethylthiazol-5-yl)pyri...)
Affinity DataKi:  670nM ΔG°:  -8.56kcal/molepH: 7.4 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed
LigandPNGBDBM8042((3-Chlorophenyl)-[4-(2,4-dimethylthiazol-5-yl)pyri...)
Affinity DataKi:  9.40E+3nM ΔG°:  -6.97kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed