BDBM7995 (3S,4S)-5-[(4-bromophenyl)methoxy]-N-cyclohexyl-3-hydroxy-4-[(2,4,6-trifluorophenyl)formamido]pentanamide::CHEMBL111720::N-[(1S,2S)-1-(4-Bromobenzyloxymethyl)-3-cyclohexylcarbamoyl-2-hydroxypropyl]-2,4,6-trifluorobenzamide::Statine-like inhibitor 34

SMILES O[C@@H](CC(=O)NC1CCCCC1)[C@H](COCc1ccc(Br)cc1)NC(=O)c1c(F)cc(F)cc1F

InChI Key InChIKey=HNRLJKSYVDQMAQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 7995   

TargetPlasmepsin II(Plasmodium falciparum)
Linkoping University

LigandPNGBDBM7995(N-[(1S,2S)-1-(4-Bromobenzyloxymethyl)-3-cyclohexyl...)
Affinity DataKi:  230nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2006
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Linkoping University

LigandPNGBDBM7995(N-[(1S,2S)-1-(4-Bromobenzyloxymethyl)-3-cyclohexyl...)
Affinity DataKi:  230nMAssay Description:Inhibitory concentration against the plasmepsin-2 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
Linkoping University

LigandPNGBDBM7995(N-[(1S,2S)-1-(4-Bromobenzyloxymethyl)-3-cyclohexyl...)
Affinity DataKi:  822nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2006
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
Linkoping University

LigandPNGBDBM7995(N-[(1S,2S)-1-(4-Bromobenzyloxymethyl)-3-cyclohexyl...)
Affinity DataKi:  822nMAssay Description:Inhibitory concentration against the plasmepsin-1 of Plasmodium falciparumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Human)
Linkoping University

LigandPNGBDBM7995(N-[(1S,2S)-1-(4-Bromobenzyloxymethyl)-3-cyclohexyl...)
Affinity DataKi: >5.90E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2006
Entry Details Article
PubMed
TargetCathepsin D(Human)
Linkoping University

LigandPNGBDBM7995(N-[(1S,2S)-1-(4-Bromobenzyloxymethyl)-3-cyclohexyl...)
Affinity DataKi: >5.90E+3nMAssay Description:Inhibitory concentration against the human Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed