BDBM7887 1-Benzylimidazole (BI)::1-benzyl-1H-imidazole::1-benzylimidazole::CHEMBL14192::US9138393, 1-benzylimidazole
SMILES C(c1ccccc1)n1ccnc1
InChI Key InChIKey=KKKDZZRICRFGSD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 7887
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of rat testis 17,20 lyase component of P450-17alphaMore data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Human)
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Shanghai University of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataKd: 1.18E+7nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human CYP4Z1 overexpressed in human MCF7 cells using luciferin-BE as substrate incubated for 24 hrs followed by substrate addition by l...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human CYP4Z1 overexpressed in human MCF7 cells using luciferin-3FBE as substrate incubated for 24 hrs followed by substrate addition by...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate after 30 mins by fluorescence-based colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 456nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human CYP11B2 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 709nMAssay Description:Inhibition of human CYP11B1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of rat testis 17-alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of rat microsomal 17-alpha-hydroxylase component of P450-17alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.91E+4nMAssay Description:Inhibition of rat microsomal 17,20-lyase component of P450-17alphaMore data for this Ligand-Target Pair
TargetCamphor 5-monooxygenase(Pseudomonas putida (g-Proteobacteria))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of wild type cytochrome P450cam expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 7.75E+4nMpH: 7.4Assay Description:All procedures were carried out under minimal light in order to prevent degradation of the retinoid samples.Microsomal preparation: one lobe of fresh...More data for this Ligand-Target Pair
Affinity DataIC50: 7.75E+4nMpH: 7.4 T: 2°CAssay Description:Microsomal preparation: One lobe of fresh pig liver is obtained (e.g., at about the time of slaughter from a food-processing company) and immediately...More data for this Ligand-Target Pair
Affinity DataKi: 262nM ΔG°: -8.97kcal/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 607nM ΔG°: -8.48kcal/molepH: 8.0 T: 2°CAssay Description:The testing for the inhibition activities of imidazole derivatives and cacodylate on gQC and sQC was evaluated at 25 C using the fluorescent substrat...More data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nM ΔG°: -7.20kcal/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nM ΔG°: -7.15kcal/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 7887
