BDBM7879 2-bromo-1-(4-methoxyphenyl)ethan-1-one::CHEMBL103009::Halomethyl Phenyl Ketone deriv. 27

SMILES COc1ccc(cc1)C(=O)CBr

InChI Key InChIKey=XQJAHBHCLXUGEP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7879   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7879(CHEMBL103009 | 2-bromo-1-(4-methoxyphenyl)ethan-1-...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qui£?Mica Medica-Csic

Curated by ChEMBL
LigandPNGBDBM7879(CHEMBL103009 | 2-bromo-1-(4-methoxyphenyl)ethan-1-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GSK3-beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM7879(CHEMBL103009 | 2-bromo-1-(4-methoxyphenyl)ethan-1-...)
Affinity DataKi:  1.28E+5nMAssay Description:Dissociation constant towards Protein-tyrosine phosphatase 1B receptor-inhibitor complex was determined using PNP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed