BDBM77051 US10093697, 7.::US10487111, Example 7.::US9694018, 7

SMILES CCCCC1(CCCC)CN(c2ccccc2)c2cc(SC)c(OCC(=O)N[C@@H](C(=O)N[C@@H](C(C)C)C(O)=O)c3ccccc3)cc2S(=O)(=O)N1

InChI Key InChIKey=AWXYVTGPUROLKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 77051   

TargetBile acid receptor(Human)
Albireo

US Patent
LigandPNGBDBM77051(US9694018, 7 | US10093697, 7. | US10487111, Exampl...)
Affinity DataIC50: 0.360nMAssay Description:ISBT Hu HEK Uptake SPA 13203 IBAT HUM Ileal Bile Acid Transporter Human HEK Glycocholic acid Uptake Radiometric SPA Inhibitor IC50 Mean IC50 (nM) was...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIleal sodium/bile acid cotransporter(Human)
TBA

US Patent
LigandPNGBDBM77051(US9694018, 7 | US10093697, 7. | US10487111, Exampl...)
Affinity DataIC50: 0.360nMAssay Description:ISBT Hu HEK Uptake SPA 13203 IBAT HUM Ileal Bile Acid Transporter Human HEK Glycocholic acid Uptake Radiometric SPA Inhibitor IC50 Mean IC50 (nM) was...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetIleal sodium/bile acid cotransporter(Human)
TBA

US Patent
LigandPNGBDBM77051(US9694018, 7 | US10093697, 7. | US10487111, Exampl...)
Affinity DataIC50: 0.360nMAssay Description:ISBT Hu HEK Uptake SPA 13203 IBAT HUM Ileal Bile Acid Transporter Human HEK Glycocholic acid Uptake Radiometric SPA Inhibitor IC50 Mean IC50 (nM) was...More data for this Ligand-Target Pair
In DepthDetails
US Patent