BDBM757015 US20250221979, Example 378

SMILES COC(=O)c1c(N)c2ccc(OC(F)(F)F)cc2n(-c2ccc([C@@H](C)O)cc2)c1=O

InChI Key InChIKey=DXWZJCYANJFKCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 757015   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandPNGBDBM757015(US20250221979, Example 378)
Affinity DataIC50: 1.20nMAssay Description:Enzymatic activity assays of compounds of this patent against MAT2A (to detect half inhibitory concentration IC50 values of the compounds) were perfo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent