BDBM7568 (2E)-3-(2-hydroxyphenyl)prop-2-enal::Cinnamaldehyde deriv. IIa

SMILES Oc1ccccc1\C=C\C=O

InChI Key InChIKey=BSDNZCQPDVTDET-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7568   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Korea Research Institute of Bioscience and Biotechnology

LigandPNGBDBM7568((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)
Affinity DataIC50: 1.30E+5nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Korea Research Institute of Bioscience and Biotechnology

LigandPNGBDBM7568((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)
Affinity DataIC50: 3.50E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2006
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM7568((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)
Affinity DataIC50: 4.70E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
National Institute of Medicinal Materials

Curated by ChEMBL
LigandPNGBDBM7568((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of xanthine oxidase- mediated uric acid formation after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed