BDBM756465 US20250215011, Example 31

SMILES CC(C)(NC(=O)CN1CC4(C1)CN(Cc3nc2c(Cl)cc(F)cc2[nH]3)C4)C(F)(F)F

InChI Key InChIKey=XNPMHMHZJGOAIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 756465   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM756465(US20250215011, Example 31)
Affinity DataIC50: 1.00E+3nMAssay Description:In some embodiments, the method of treating a depressive disorder, e.g., major depressive disorder, provides a therapeutic effect (e.g., as measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
Go to US Patent