BDBM7532 BAY 59-7939 Analog 10::US8822458, 11

SMILES Fc1cc(ccc1N1CCNCC1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O

InChI Key InChIKey=RCVMZVZBCGIKNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7532   

TargetCoagulation factor X(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM7532(BAY 59-7939 Analog 10 | US8822458, 11)
Affinity DataIC50: 140nMT: 2°CAssay Description:The enzymatic activity of human factor Xa (FXa) was measured using the conversion of a chromogenic substrate specific for FXa. Factor Xa cleaves p-ni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent

TargetCoagulation factor X(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM7532(BAY 59-7939 Analog 10 | US8822458, 11)
Affinity DataIC50: 140nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed