BDBM73215 7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacyclopentadecane;2,2,2-trifluoroacetic acid::7,13-bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane;2,2,2-trifluoroacetic acid::7,13-bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane;2,2,2-tris(fluoranyl)ethanoic acid::CHEMBL1401670::VU0277590-7::cid_44176372

SMILES [O-][N+](=O)c1ccc(CN2CCOCCOCCN(Cc3ccc(cc3)[N+]([O-])=O)CCOCC2)cc1

InChI Key InChIKey=UKMHVECLTZDSBD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 73215   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM73215(VU0277590-7 | 7,13-bis[(4-nitrophenyl)methyl]-1,4,...)
Affinity DataIC50: 273nMAssay Description:Assay Provider: Jerod Denton Assay Provider Affiliation: Vanderbilt University Grant Title: High throughput discovery of novel modulators of ROMK K+ ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM73215(VU0277590-7 | 7,13-bis[(4-nitrophenyl)methyl]-1,4,...)
Affinity DataIC50: 290nMAssay Description:Inhibition of ROMKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rat)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM73215(VU0277590-7 | 7,13-bis[(4-nitrophenyl)methyl]-1,4,...)
Affinity DataIC50: 294nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed