BDBM722467 N-(4-(4-amino- 7-(1-(2- hydroxyethyl)- 1H-pyrazol-4- yl)furo[3,2-c] pyridin-3-yl)- 2-((4- fluorobenzyl) oxy)phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 6

SMILES Nc1ncc(-c2cnn(CCO)c2)c2occ(-c3ccc(NS(=O)(=O)C(F)F)c(OCc4ccc(F)cc4)c3)c12

InChI Key InChIKey=MVJDMVJOPGZDCA-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 722467   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722467(N-(4-(4-amino- 7-(1-(2- hydroxyethyl)- 1H-pyrazol-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722467(N-(4-(4-amino- 7-(1-(2- hydroxyethyl)- 1H-pyrazol-...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722467(N-(4-(4-amino- 7-(1-(2- hydroxyethyl)- 1H-pyrazol-...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent