BDBM716749 US20250034135, Compound 187

SMILES CC(C)c1ccccc1[C@@H]1CN(Cc2ccc(F)cc2)CCN1C1CC2(CCN(c3cc(Oc4cnc5[nH]ccc5c4)c(C(=O)NS(=O)(=O)c4ccc(NCC5(F)CCOCC5)c([N+](=O)[O-])c4)cc3F)CC2)C1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 716749   

TargetApoptosis regulator Bcl-2(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716749(US20250034135, Compound 187)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716749(US20250034135, Compound 187)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent