BDBM716748 US20250034135, Compound 186

SMILES COc1ccccc1CN1CCN(C2CC3(CCN(c4cc(Oc5cnc6[nH]ccc6c5)c(C(=O)NS(=O)(=O)c5ccc(NCC6(F)CCOCC6)c([N+](=O)[O-])c5)cc4F)CC3)C2)[C@H](c2ccccc2C(C)C)C1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 716748   

TargetApoptosis regulator Bcl-2(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716748(US20250034135, Compound 186)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2 [G101V](Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716748(US20250034135, Compound 186)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716748(US20250034135, Compound 186)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent