BDBM716564 US20250034135, Compound 002

SMILES CC(C)c1ccccc1[C@@H]2CCCN2C%11CC%10(CCN(c9ccc(C(=O)NS(=O)(=O)c5cc([N+](=O)[O-])c(CCC4(F)CCN(C3COC3)CC4)c6[nH]cnc56)c(Oc8cnc7[nH]ccc7c8)c9)CC%10)C%11

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 716564   

TargetApoptosis regulator Bcl-2(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716564(US20250034135, Compound 002)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2 [G101V](Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716564(US20250034135, Compound 002)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716564(US20250034135, Compound 002)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716564(US20250034135, Compound 002)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716564(US20250034135, Compound 002)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent