BDBM716163 6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-methyl-5- (trifluoromethyl)phenyl)- cyclohexyl)oxy)-2-methyl-N- (pyrimidin-4-yl)pyridine-3- sulfonamide::US12209075, Example 58

SMILES Cc1cc([C@H]2CC[C@H](Oc3ccc(S(=O)(=O)Nc4ccncn4)c(C)n3)[C@@H](N(C)C)C2)cc(C(F)(F)F)c1

InChI Key InChIKey=TURAEZDSWZCNQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716163   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM716163(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(3-methyl-5- ...)
Affinity DataIC50: 0.351nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent