BDBM716148 6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-fluoro-5- (trifluoromethyl)phenyl)- cyclohexyl)oxy)-2-methyl-N- (pyrimidin-4-yl)pyridine-3- sulfonamide formate::US12209075, Example 43

SMILES Cc1nc(O[C@H]2CC[C@H](c3cc(C(F)(F)F)ccc3F)C[C@@H]2N(C)C)ccc1S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=QSKVFPDBZZPJBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716148   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM716148(6-(((1S,2S,4S)-2-(dimethyl- amino)-4-(2-fluoro-5- ...)
Affinity DataIC50: 0.687nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent