BDBM716131 N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2-(1-piperidyl)-4- [3-(trifluoromethyl)phenyl]- cyclohexoxy]pyridine-3- sulfonamide::US12209075, Example 26

SMILES O=S(=O)(Nc1ccncn1)c1ccc(O[C@H]2CC[C@H](c3cccc(C(F)(F)F)c3)C[C@@H]2N2CCCCC2)nc1

InChI Key InChIKey=XACZFSZWPHKLBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716131   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM716131(N-pyrimidin-4-yl-6-[rac- (1S,2S,4S)-2-(1-piperidyl...)
Affinity DataIC50: 1.16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent