BDBM716123 5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-pyrrolidin- 1-yl-4-[3-(trifluoromethyl)- phenyl]cyclohexoxy]pyridine- 3-sulfonamide::US12209075, Example 18

SMILES O=S(=O)(Nc1ccncn1)c1cnc(O[C@H]2CC[C@H](c3cccc(C(F)(F)F)c3)C[C@@H]2N2CCCC2)c(Cl)c1

InChI Key InChIKey=JHEYBWJZRDYLPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716123   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM716123(5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2-pyr...)
Affinity DataIC50: 0.388nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent