BDBM715721 5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2- (dimethylamino)-4-[3- (trifluoromethyl)phenyl]- cyclohexoxy]pyridine-3- sulfonamide formate salt::US12209075, Example 3

SMILES CN(C)[C@H]1C[C@@H](c2cccc(C(F)(F)F)c2)CC[C@@H]1Oc1ncc(S(=O)(=O)Nc2ccncn2)cc1Cl

InChI Key InChIKey=JDSFVOKEEIJXEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715721   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM715721(5-chloro-N-pyrimidin-4-yl-6- [rac-(1S,2S,4S)-2- (d...)
Affinity DataIC50: 2.21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
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