BDBM713013 US20250019385, Example II-2

SMILES C[C@H](Oc1nc(-c2noc3c2CCC[C@@]32CCCc3sc(N)c(C#N)c32)nc2c1n(C)c(=O)n2[C@@H]1CCOC1)[C@@H]1CCCN1C

InChI Key

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 713013   

TargetGTPase KRas [1-169,G12D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetGTPase KRas [1-169,G12C,C51S,C80L,C118S]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetGTPase KRas [1-169]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetGTPase KRas [1-169,G12V,C118S]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetGTPase KRas [1-169,G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetGTPase KRas [1-169]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetGTPase KRas [1-169,G12V,C118S]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetGTPase KRas [1-169,G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM713013(US20250019385, Example II-2)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent