BDBM709654 4-methoxy-6-(1-(1- (1- (vinylsulfonyl)piperi- dine-4- carbonyl)piperidin- 4-yl)-1H-pyrazol-4- yl)pyrazolo[1,5- a]pyridine-3- carbonitrile::US12180207, Example 186

SMILES C=CS(=O)(=O)N1CCC(C(=O)N2CCC(n3cc(-c4cc(OC)c5c(C#N)cnn5c4)cn3)CC2)CC1

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 709654   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709654(4-methoxy-6-(1-(1- (1- (vinylsulfonyl)piperi- dine...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709654(4-methoxy-6-(1-(1- (1- (vinylsulfonyl)piperi- dine...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709654(4-methoxy-6-(1-(1- (1- (vinylsulfonyl)piperi- dine...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM709654(4-methoxy-6-(1-(1- (1- (vinylsulfonyl)piperi- dine...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709654(4-methoxy-6-(1-(1- (1- (vinylsulfonyl)piperi- dine...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent