BDBM709616 (E)-6-(1-(1-((1-(4- (dimethylamino)but-2- enoyl)azetidin-3- yl)methyl)piperidin- 4-yl)-1H-pyrazol- 4-yl)-4-methoxypyrazolo [1,5-a]pyridine-3-carbonitrile::US12180207, Example 146

SMILES COc1cc(-c2cnn(C3CCN(CC4CN(C(=O)/C=C/CN(C)C)C4)CC3)c2)cn2ncc(C#N)c12

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 709616   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709616((E)-6-(1-(1-((1-(4- (dimethylamino)but-2- enoyl)az...)
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709616((E)-6-(1-(1-((1-(4- (dimethylamino)but-2- enoyl)az...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709616((E)-6-(1-(1-((1-(4- (dimethylamino)but-2- enoyl)az...)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM709616((E)-6-(1-(1-((1-(4- (dimethylamino)but-2- enoyl)az...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709616((E)-6-(1-(1-((1-(4- (dimethylamino)but-2- enoyl)az...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent