BDBM709515 N-((1s,3s)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,5- a]pyridin-6-yl)-1H- pyrazol-1-yl)piperidine-1- carbonyl)cyclobutyl)acryl- amide::US12180207, Example 44

SMILES C=CC(=O)N[C@H]1C[C@@H](C(=O)N2CCC(n3cc(-c4cc(OC)c5c(C#N)cnn5c4)cn3)CC2)C1

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 709515   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709515(N-((1s,3s)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 97nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709515(N-((1s,3s)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709515(N-((1s,3s)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM709515(N-((1s,3s)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709515(N-((1s,3s)-3-(4-(4-(3- cyano-4- methoxypyrazolo[1,...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent