BDBM709478 6-(1-(1-((1S,5S)-6- acryloyl-3,6- diazabicyclo[3.2.0]heptane- 3-carbonyl)piperidin-4- yl)-1H-pyrazol-4-yl)-4- methoxypyrazolo[1,5- a]pyridine-3-carbonitrile::US12180207, Example 7

SMILES C=CC(=O)N1C[C@H]2CN(C(=O)N3CCC(n4cc(-c5cc(OC)c6c(C#N)cnn6c5)cn4)CC3)C[C@H]21

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 709478   

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709478(6-(1-(1-((1S,5S)-6- acryloyl-3,6- diazabicyclo[3.2...)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709478(6-(1-(1-((1S,5S)-6- acryloyl-3,6- diazabicyclo[3.2...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Array Biopharma

US Patent
LigandPNGBDBM709478(6-(1-(1-((1S,5S)-6- acryloyl-3,6- diazabicyclo[3.2...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Array Biopharma

US Patent
LigandPNGBDBM709478(6-(1-(1-((1S,5S)-6- acryloyl-3,6- diazabicyclo[3.2...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Array Biopharma

US Patent
LigandPNGBDBM709478(6-(1-(1-((1S,5S)-6- acryloyl-3,6- diazabicyclo[3.2...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent