BDBM708073 (R)-2-(3- carbamoylpyrrolidin-1-yl)- 5-hydroxy-N-(isoxazol-4- yl)-1-methyl-6-oxo-1,6- dihydropyrimidine-4- carboxamide::US12172990, Example 118

SMILES Cn1c(N2CC[C@@H](C(N)=O)C2)nc(C(=O)Nc2cnoc2)c(O)c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708073   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708073((R)-2-(3- carbamoylpyrrolidin-1-yl)- 5-hydroxy-N-(...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708073((R)-2-(3- carbamoylpyrrolidin-1-yl)- 5-hydroxy-N-(...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent