BDBM708049 (S)-2-(1-(3-chloro-4- fluorobenzoyl)piperidin-3-yl)-5- hydroxy-N-(isoxazol-4-yl)-1- methyl-6-oxo-1,6- dihydropyrimidine-4-carboxamide::US12172990, Example 88

SMILES Cn1c([C@H]2CCCN(C(=O)c3ccc(F)c(Cl)c3)C2)nc(C(=O)Nc2cnoc2)c(O)c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708049   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708049((S)-2-(1-(3-chloro-4- fluorobenzoyl)piperidin-3-yl...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708049((S)-2-(1-(3-chloro-4- fluorobenzoyl)piperidin-3-yl...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent