BDBM708035 2-(5-bromo-2-(2- hydroxyethoxy) phenyl)-5-hydroxy-N- (isoxazol-4-yl)-1- methyl-6-oxo-1,6- dihydropyrimidine-4- carboxamide::US12172990, Example 70

SMILES Cn1c(-c2cc(Br)ccc2OCCO)nc(C(=O)Nc2cnoc2)c(O)c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708035   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708035(2-(5-bromo-2-(2- hydroxyethoxy) phenyl)-5-hydroxy-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708035(2-(5-bromo-2-(2- hydroxyethoxy) phenyl)-5-hydroxy-...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent