BDBM708000 5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl-5- (4-methylpiperazin-1- yl)phenyl)-6-oxo-1,6- dihydropyrimidine-4- carboxamide::US12172990, Example 33

SMILES Cc1cc(-c2nc(C(=O)Nc3cnoc3)c(O)c(=O)n2C)cc(N2CCN(C)CC2)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708000   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708000(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM708000(5-hydroxy-N- (isoxazol-4-yl)-1- methyl-2-(3-methyl...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent