BDBM707995 5-hydroxy-N-(isoxazol-4-yl)-1-methyl-6-oxo-2-(piperidin-1-yl)-1,6-dihydropyrimidine-4-carboxamide::US12172990, Example 28

SMILES Cn1c(N2CCCCC2)nc(C(=O)NC2C=NOC2)c(O)c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707995   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707995(5-hydroxy-N-(isoxazol-4-yl)-1-methyl-6-oxo-2-(pipe...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707995(5-hydroxy-N-(isoxazol-4-yl)-1-methyl-6-oxo-2-(pipe...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent