BDBM707985 US12172990, Example 18::tert-butyl 3-((5- hydroxy-4-(isoxazol- 4-ylcarbamoyl)-1- methyl-6-oxo-1,6- dihydropyrimidin-2- yl)methyl)piperidine- 1-carboxylate

SMILES Cn1c(CC2CCCN(C(=O)OC(C)(C)C)C2)nc(C(=O)Nc2cnoc2)c(O)c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707985   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707985(tert-butyl 3-((5- hydroxy-4-(isoxazol- 4-ylcarbamo...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707985(tert-butyl 3-((5- hydroxy-4-(isoxazol- 4-ylcarbamo...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent