BDBM707983 US12172990, Example 16::tert-butyl 3-(5- hydroxy-4-(isoxazol- 4-ylcarbamoyl)-6-oxo- 1,6-dihydropyrimidin- 2-yl)piperidine-1- carboxylate

SMILES CC(C)(C)OC(=O)N1CCCC(c2nc(C(=O)Nc3cnoc3)c(O)c(=O)[nH]2)C1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707983   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707983(tert-butyl 3-(5- hydroxy-4-(isoxazol- 4-ylcarbamoy...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707983(tert-butyl 3-(5- hydroxy-4-(isoxazol- 4-ylcarbamoy...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent