BDBM707969 2-cyclobutyl-5- hydroxy-N-(isoxazol- 4-yl)-1-methyl-6-oxo- 1,6- dihydropyrimidine-4- carboxamide::US12172990, Example 2

SMILES Cn1c(C2CCC2)nc(C(=O)Nc2cnoc2)c(O)c1=O

InChI Key InChIKey=VNVQXARVGKVXON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707969   

TargetThree-prime repair exonuclease 1(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707969(2-cyclobutyl-5- hydroxy-N-(isoxazol- 4-yl)-1-methy...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent

TargetThree prime repair exonuclease 2(Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM707969(2-cyclobutyl-5- hydroxy-N-(isoxazol- 4-yl)-1-methy...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/5/2025
Entry Details
Go to US Patent