BDBM707531 US20240409609, Compound 57

SMILES CN1CCN(Cc2ccc3[nH]/c(=N\C(=O)c4ccnc(C#Cc5c(F)ccc(O)c5C=O)c4)n(CC(C)(C)O)c3c2)CC1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 707531   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Terremoto Biosciences

US Patent
LigandPNGBDBM707531(US20240409609, Compound 57)
Affinity DataIC50: 2.44nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor [T790M,C797S,L858R](Homo sapiens (Human))
Terremoto Biosciences

US Patent
LigandPNGBDBM707531(US20240409609, Compound 57)
Affinity DataIC50: 0.315nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Terremoto Biosciences

US Patent
LigandPNGBDBM707531(US20240409609, Compound 57)
Affinity DataIC50: 6.03nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent