BDBM707392 2-(4-{2-[(S)-2-methyl-1- azetidinyl]-6-(difluoromethyl)-5- ethyl-4-pyrimidinyl}-1-pyrazolyl)- 1-(1-piperazinyl)-1-ethanone::US20240409530, Compound A26

SMILES CCc1c(-c2cnn(CC(=O)N3CCNCC3)c2)nc(N2CC[C@@H]2C)nc1C(F)F

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 707392   

TargetKetohexokinase(Human)
Centennial Therapeutics

US Patent
LigandPNGBDBM707392(2-(4-{2-[(S)-2-methyl-1- azetidinyl]-6-(difluorome...)
Affinity DataIC50: 32.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Centennial Therapeutics

US Patent
LigandPNGBDBM707392(2-(4-{2-[(S)-2-methyl-1- azetidinyl]-6-(difluorome...)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Rat)
Centennial Therapeutics

US Patent
LigandPNGBDBM707392(2-(4-{2-[(S)-2-methyl-1- azetidinyl]-6-(difluorome...)
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Rattus norvegicus (Rat))
Centennial Therapeutics

US Patent
LigandPNGBDBM707392(2-(4-{2-[(S)-2-methyl-1- azetidinyl]-6-(difluorome...)
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent