BDBM707391 (2R,3R)-1-{4-[1-(1-methyl-3- azetidinyl)-4-pyrazolyl]-6- (trifluoromethyl)-2-pyrimidinyl}- 2-(trifluoromethyl)-3-azetidinol::US20240409530, Compound A25

SMILES CN1CC(n2cc(-c3cc(C(F)(F)F)nc(N4C[C@@H](O)[C@@H]4C(F)(F)F)n3)cn2)C1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 707391   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM707391((2R,3R)-1-{4-[1-(1-methyl-3- azetidinyl)-4-pyrazol...)
Affinity DataIC50: 5.22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

LigandPNGBDBM707391((2R,3R)-1-{4-[1-(1-methyl-3- azetidinyl)-4-pyrazol...)
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

TargetKetohexokinase(Rat)TBA
LigandPNGBDBM707391((2R,3R)-1-{4-[1-(1-methyl-3- azetidinyl)-4-pyrazol...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails

TargetIsoform A of Ketohexokinase (Peripheral)(Rattus norvegicus (Rat))TBA
LigandPNGBDBM707391((2R,3R)-1-{4-[1-(1-methyl-3- azetidinyl)-4-pyrazol...)
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails