BDBM707368 2-(4-{2-[(R)-2-(trifluoromethyl)-1- azetidinyl]-6-(trifluoromethyl)-4- pyrimidinyl}-1-pyrazolyl)-1-(1- piperazinyl)-1-ethanone::US20240409530, Compound A2

SMILES O=C(Cn1cc(-c2cc(C(F)(F)F)nc(N3CC[C@@H]3C(F)(F)F)n2)cn1)N1CCNCC1

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 707368   

TargetKetohexokinase(Human)
Centennial Therapeutics

US Patent
LigandPNGBDBM707368(2-(4-{2-[(R)-2-(trifluoromethyl)-1- azetidinyl]-6-...)
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Centennial Therapeutics

US Patent
LigandPNGBDBM707368(2-(4-{2-[(R)-2-(trifluoromethyl)-1- azetidinyl]-6-...)
Affinity DataIC50: 13.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetKetohexokinase(Rat)
Centennial Therapeutics

US Patent
LigandPNGBDBM707368(2-(4-{2-[(R)-2-(trifluoromethyl)-1- azetidinyl]-6-...)
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Rattus norvegicus (Rat))
Centennial Therapeutics

US Patent
LigandPNGBDBM707368(2-(4-{2-[(R)-2-(trifluoromethyl)-1- azetidinyl]-6-...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
Go to US Patent