BDBM704699 US20240376080, Compound 4S

SMILES [2H]C([2H])([2H])NC(=O)c1cnc(NC(=O)[C@H]2CC23CC3)cc1Nc1cccc(-c2ncn(C)n2)c1OC

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 704699   

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Zhejiang Wenda Pharmaceutical Technology

US Patent
LigandPNGBDBM704699(US20240376080, Compound 4S)
Affinity DataIC50: 9.95E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Zhejiang Wenda Pharmaceutical Technology

US Patent
LigandPNGBDBM704699(US20240376080, Compound 4S)
Affinity DataIC50: 0.120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [861-1152](Human)
Zhejiang Wenda Pharmaceutical Technology

US Patent
LigandPNGBDBM704699(US20240376080, Compound 4S)
Affinity DataIC50: 9.95E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Zhejiang Wenda Pharmaceutical Technology

US Patent
LigandPNGBDBM704699(US20240376080, Compound 4S)
Affinity DataIC50: 1.66nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [831-1132](Human)
Zhejiang Wenda Pharmaceutical Technology

US Patent
LigandPNGBDBM704699(US20240376080, Compound 4S)
Affinity DataIC50: 9.95E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Zhejiang Wenda Pharmaceutical Technology

US Patent
LigandPNGBDBM704699(US20240376080, Compound 4S)
Affinity DataIC50: 9.95E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent