BDBM704439 5-Methoxy-6-(1-methylbenzimidazol-4-yl)-3-(4-morpholinoanilino)pyrazine-2-carboxamide::US20240374606, Example 3

SMILES COc1nc(Nc2ccc(N3CCOCC3)cc2)c(C(N)=O)nc1-c1cccc2c1ncn2C

InChI Key InChIKey=BSHKOVUWWILTRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 704439   

LigandPNGBDBM704439(5-Methoxy-6-(1-methylbenzimidazol-4-yl)-3-(4-morph...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent

LigandPNGBDBM704439(5-Methoxy-6-(1-methylbenzimidazol-4-yl)-3-(4-morph...)
Affinity DataIC50: 154nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Lck(Human)
Astrazeneca

US Patent
LigandPNGBDBM704439(5-Methoxy-6-(1-methylbenzimidazol-4-yl)-3-(4-morph...)
Affinity DataIC50: 3.84E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent