BDBM703923 N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl]-6- (cyclopropylamino)pyrimidine-4- carboxamide. LCMS [M + 1]+ = 350.2. 1H NMR (400 MHz, CDCl3) $#948; ppm 8.67 (d, J = 2.0 Hz, 1 H) 8.36-8.59 (m, 2 H) 7.86 (d, J = 2.0 Hz, 1 H) 7.49 (br s, 1 H) 6.79 (d, J = 0.8 Hz, 1 H) 5.45-5.83 (m, 1 H) 4.86-5.12 (s, 2 H) 4.82 (d, J = 6.0 Hz, 2 H) 2.60-2.71 (m, 4 H) 0.90-1.00 (m, 2 H) 0.61-0.67 (m, 2 H).::US20240368153, Example 7-4

SMILES Cc1cc(N)nc2cc(CNC(=O)c3cc(NC4CC4)ncn3)cnc12

InChI Key

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 703923   

LigandPNGBDBM703923(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703923(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataKd:  22nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703923(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataKd:  81nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703923(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 1.66E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703923(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 1.82E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent