BDBM703922 N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl]-6-hydroxy-pyrimidine-4- carboxamide. LCMS [M + 1]+ = 311.1. 1H NMR (400 MHz, CD3OD) $#948; = 8.81 (d, J = 1.6 Hz, 1H), 8.32 (s, 1H), 7.99 (d, J = 1.6 Hz, 1H), 7.13 (d, J = 1.2 Hz, 1H), 7.10 (s, 1H), 4.78 (s, 2H), 2.75 (d, J = 1.2 Hz, 3H).::US20240368153, Example 7-3

SMILES Cc1cc(N)nc2cc(CNC(=O)c3cc(O)ncn3)cnc12

InChI Key

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 703922   

LigandPNGBDBM703922(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 1.06E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703922(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataKd:  682nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703922(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataKd:  1.25E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703922(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 6.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

LigandPNGBDBM703922(N-[(6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent