BDBM703915 6-(2-fluorophenyl)-4-methyl-1,5-naphthyridin-2- amine. LCMS [M + 1] = 254.3. 1H NMR (400 MHz, MeOD) $#948; = 8.10 (dt, J = 1.8, 8.0 Hz, 1H), 7.97- 7.92 (m, 1H), 7.90-7.85 (m, 1H), 7.49-7.40 (m, 1H), 7.34-7.28 (t, J = 7.6, 1H), 7.26-7.19 (m, 1H), 6.95 (d, J = 1.2 Hz, 1H), 2.70 (d, J = 0.8 Hz, 3H).::US20240368153, Example 4-7

SMILES Cc1cc(N)nc2ccc(-c3ccccc3F)nc12

InChI Key

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 703915   

LigandPNGBDBM703915(6-(2-fluorophenyl)-4-methyl-1,5-naphthyridin-2- am...)
Affinity DataIC50: 1.01E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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LigandPNGBDBM703915(6-(2-fluorophenyl)-4-methyl-1,5-naphthyridin-2- am...)
Affinity DataKd:  3.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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LigandPNGBDBM703915(6-(2-fluorophenyl)-4-methyl-1,5-naphthyridin-2- am...)
Affinity DataKd:  8.14E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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LigandPNGBDBM703915(6-(2-fluorophenyl)-4-methyl-1,5-naphthyridin-2- am...)
Affinity DataIC50: 3.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703915(6-(2-fluorophenyl)-4-methyl-1,5-naphthyridin-2- am...)
Affinity DataIC50: 3.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent