BDBM703895 2-((6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl)benzonitrile. LCMS [M + 1]: 275.2. 1H NMR (400 MHz, MeOD-d4) $#948; = 8.51 (d, J = 2.0 Hz, 1H), 7.77 (d, J = 7.6 Hz, 1H), 7.71-7.63 (m, 2H), 7.56 (d, J = 7.8 Hz, 1H), 7.49-7.42 (m, 1H), 6.90 (d, J = 0.8 Hz, 1H), 4.40 (s, 2H), 2.62 (d, J = 1.2 Hz, 3H).::US20240368153, Example 2-4

SMILES Cc1cc(N)nc2cc(Cc3ccccc3C#N)cnc12

InChI Key

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 703895   

LigandPNGBDBM703895(2-((6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 992nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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LigandPNGBDBM703895(2-((6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataKd:  874nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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LigandPNGBDBM703895(2-((6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataKd:  3.09E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703895(2-((6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 3.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM703895(2-((6-amino-8-methyl-1,5-naphthyridin-3- yl)methyl...)
Affinity DataIC50: 3.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent