BDBM703748 2-[1-[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)phen- yl]piperazin-1-yl]- ethyl]-5-methyl- thiazole::US20240368133, Compound A-225

SMILES Cc4cnc(C(C)N3CCN(c1cc(CC(C)C)cc(F)c1c2nn[nH]n2)CC3)s4

InChI Key InChIKey=AKHATAQDINXUIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703748   

LigandPNGBDBM703748(2-[1-[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl...)
Affinity DataIC50: 54.1nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent